Recommended Reading : Curing the Incurable Vitamin C, Infectious Diseases and Toxins
by Thomas E. Levy, MD, JD (with over 1,200 scientific references)

Vitamin C has been known to have anti viral activity since 1936. There are case studies showing Vitamin C to have anti viral effect on the Common Cold virus, the Herpes virus, the Cytomegalo Virus, Influenza Virus, Polio Virus, Viral Hepatitis, Measels, Mumps, Viral Encephalitis, Chickenpox, Viral Pneumonia, Rabies, AIDS, HIV, Ebola Virus, and many more viruses including SARS and Avian Bird Flu. Other non-viral diseases can also be cured by therapeutic doses of Vitamin C, such as Diptheria, Whooping Cough, Tetanus, Tuberculosis, Streptococcal Infections, Leprosy, Typhoid Fever, Malaria, Brucellosis, Trichinosis, Amebic Dysentery, Rocky Mountain Spotted Fever, Staphlococcal Infections, and others. As much as 6,000 to 30,000 mg would be given intravenously or intramuscularly in a 24 hour period for 2-3 days with no residual damage. This would get tissue levels of Vitamin C up to an optimum range of Vitamin C more effectively than only oral administration. But oral doses were also included.

The “natural killer cells,” called NK cells, are the “search and destroy” cells of the immune system. They search out viruses, bacteria and other foreign invaders, as well as altered cells such as cancer cells. After finding them, they act to kill them. These cells have molecular pumps on their surfaces that concentrate ascorbic acid in order to form hydrogen peroxide, amongst other things, in order to carry out this activity. This is just one way in which ascorbic acid acts as an immune stimulant.

During an infection, there is a “storm of free radical generation”. It is the damaging effects of free radicals on cell membranes and structural molecules such as collagen that severely disrupts cellular functioning. This produces the tissue effects seen specific to the organ system in which the infection occurs. The body has its own enzyme system that neutralizes one type of free radical molecule – the superoxide molecule which is neutralized by the selenium dependant super oxide dismutase enzyme. This likely explains, at least in part, the clinical observation that selenium added to a nutritional strategy in viral infections such as Hepatitis and HIV improves outcome. But the selenium-SOD system is specific to the superoxide radical and ineffective against other radical oxygen species. Vitamin C is nature's premier antioxidant scavenger that stops free radical damage.

All human beings have a genetic disease of Vitamin C. They lack the enzyme gulano lactate oxidase which finalizes the conversion of glucose to ascorbic acid (Vitamin C). Nearly all organisms on earth have an enzyme system that converts glucose into the vital nutrient ascorbic acid. Humans, the higher primates, the guinea pug, and the fruit bat all have genetic mutations which interferes with the cells ability to make ascorbic acid, thus making it imperative that they take in adequate amounts in their diet or as a supplement. In order to maintain cellular levels of Vitamin C, it is important to “pulse” doses of Vitamin C throughout the day. Remember that all organisms, except those mentioned above, continuously make Vitamin C from glucose in order to keep levels high. In humans, a dose of Vitamin C will last for 6 hours in the blood, this is the rationale for the “flow through” model of frequent dosing of this all important vitamin.

In all cases, in order for an effect to be seen, dosage and frequency of administration is of critical importance. A gram dose (1000 mg = 1 gram) of Vitamin C has been shown to have minimal effects on the progress of the common cold and presumably would have little effect on more invasive, pathologic viruses. A sustained intake of higher doses in the 2 to 5 gram range has been shown to have moderate effects. High levels of 10 to 70 grams may be required for effect on virulent infections. Case studies indicate that intravenous Ascorbic Acid is effective in serious viral infections.

An easy way of obtaining optimal levels of Vitamin C is to take 1000 mg (1 gram) with each meal and at bedtime. This gives a person the 4 gram amount that is found in animals which naturally synthesize this vitamin every day. During times of infection, the dosage and frequency of Vitamin C should be increased to 2-5 grams every 2 to 4 hours. During a 24 hour period, 30-75 grams of Vitamin C may be required. Again, this is the amount that animals make under the stress of infection. At these high doses, there may be some gastric upset, gas or diarrhea. If this happens, simply reduce the amount of the next dose. Drink plenty of liquids with these doses of Vitamin C. Vitamin C helps to improve the effectiveness of many other therapies, including antibiotics, if they are needed.

Take ¼ teaspoon (1000 mg) to 1 teaspoon (4000 mg) of powdered ascorbic acid and add to warm water that helps dissolve the powder. Stir until dissolved. Add to your favourite juice. You may wish to further water down the juice. By sipping this drink over an hour or more one will increase the absorption of the vitamin without gastric upset. Remember in cases of severe infections to repeat this every few hours.

Vitamin C can be administered intravenously by a Medical Doctor who practises Complimentary Medicine. Further information can be found in the book mentioned above.

Vitamin C in Health & Disease , Packer & Fuchs (1997)
Ascorbate: The Science of Vitamin C , Hickey & Roberts (2004)
Vitamin C, Infectious Diseases and Toxins , Levy (2002)
Vitamin C, Its Chemistry & Biochemistry , Davies (1991)